Properties: mol wt 70,000-150,000 by viscosity

Poly-L-lysine polymers can be used in promoting cell adhesion to solid substrates, conjugation to methotrexate for increased drug transport, microencapsulation of islets, cell microencapsulation technology, microarray glass slide coating, and chromosomal preparations. Lower molecular weight poly-L-lysine (30,000-70,000) is less viscuous in solution, but higher molecular weight versions provide more attachment sites per molecule.

Poly-L-lysine hydrobromide is used for the following applications:
• Used for some experiments with REF-52 cells, for coating[1]
• For electrophysiological experiments, cells were seeded on poly-L-lysine hydrobromide coated or uncoated cover-slips[2][5]
• Cell culture of rat neurons[4]
• Indirect binding of monoclonal antibody via poly-llysine[3]


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